Role of rhBMP-7, Fibronectin, And Type I Collagen in Dental Implant Osseointegration Process: An Initial Pilot Study on Minipig Animals.

Gianmario SchieranoRosa Angela CanutoMauthe Degerfeld MitzyRoberto NavoneBruno PeironeGiulio PretiGiuliana Muzio

Published in: Materials (Basel, Switzerland) (2021)

This initial pilot study, in a novel way, evidenced that Type 1 Collagen induced inflammation and did not stimulate bone production; conversely FN or rhBMP-7 showed neo-osteogenetic and anti-inflammatory properties when directly added into implant bone site.

Keyphrases

soft tissue
bone mineral density
anti inflammatory
oxidative stress
diabetic rats
bone loss
wound healing
recombinant human
high glucose
bone regeneration
postmenopausal women
oral health
type iii
stress induced