Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy.
Mayarling Francisca TroncosoMario PavezCarlos WilsonDaniel LagosJavier DuranSebastián RamosGenaro BarrientosPatricio SilvaPaola LlanosCarla Basualto-AlarcónB Daan WestenbrinkSergio LavanderoManuel EstradaPublished in: Biological research (2021)
These results indicate that testosterone stimulates glucose metabolism by activation of AMPK and AR signaling which are critical to induce cardiomyocyte hypertrophy.