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Exploring the effects of extended interval dosing of natalizumab and drug concentrations on brain atrophy in multiple sclerosis.

Alyssa A TooropSamantha NoteboomMartijn D SteenwijkJob W GravendeelBas JasperseFrederik BarkhofEva M M StrijbisTheo RispensMenno Michiel SchoonheimZoé Léonie Elise van KempenJoep Killestein
Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)
We found no clear evidence that EID compared to SID or lower natalizumab drug concentrations have a negative impact on the development of brain atrophy over time.
Keyphrases
  • multiple sclerosis
  • white matter
  • resting state
  • functional connectivity
  • adverse drug
  • cerebral ischemia
  • emergency department
  • brain injury
  • blood brain barrier