Clonal Hematopoiesis of Indeterminate Potential in Chronic Thromboembolic Pulmonary Hypertension: A Multicenter Study.

Chao LiuYu-Ping Zhou Tian-Yu LianRuo-Nan LiJing-Si Ma Yin-Jian Yang Si-Jin Zhang Xian-Mei Li Lu-Hong Qiu Bao-Chen Qiu Li-Yan Ren Jia WangZhi-Yan HanJing-Hui LiLan WangXi-Qi XuKai SunLian-Feng Chen Chun-Yan Cheng Ze-Jian Zhang Zhi-Cheng Jing

Published in: Hypertension (Dallas, Tex. : 1979) (2023)

This is the first study to show that CHIP mutations occurred in 9.4% of patients with CTEPH are associated with a severe inflammatory state and confer a poorer prognosis in long-term follow-up.

Keyphrases

pulmonary hypertension
oxidative stress
high throughput
early onset
pulmonary artery
pulmonary arterial hypertension
atrial fibrillation
drug induced
human health
climate change
hematopoietic stem cell