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Plasma neurofilament light levels are associated with risk of disability in multiple sclerosis.

Ali ManouchehriniaPernilla StridhMohsen KhademiDavid LeppertChristian BarroZuzanna MichalakPascal BenkertJan LyckeLars AlfredssonLudwig KapposFredrik PiehlTomas OlssonJens KuhleIngrid Kockum
Published in: Neurology (2020)
Elevated pNfL levels at early stages of MS are associated with an increased risk of reaching sustained disability worsening. Hence, pNfL may serve as a prognostic tool to assess the risk of developing permanent disability in MS.
Keyphrases
  • multiple sclerosis
  • white matter
  • mass spectrometry
  • cerebrospinal fluid