Plasma neurofilament light levels are associated with risk of disability in multiple sclerosis.
Ali ManouchehriniaPernilla StridhMohsen KhademiDavid LeppertChristian BarroZuzanna MichalakPascal BenkertJan LyckeLars AlfredssonLudwig KapposFredrik PiehlTomas OlssonJens KuhleIngrid KockumPublished in: Neurology (2020)
Elevated pNfL levels at early stages of MS are associated with an increased risk of reaching sustained disability worsening. Hence, pNfL may serve as a prognostic tool to assess the risk of developing permanent disability in MS.