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Pd(II)-Catalyzed oxidative alkenylation of 4-hydroxycoumarin with maleimide via a C-H bond activation strategy.

Kumud SharmaKashmiri NeogAbhilash SharmaPranjal Gogoi
Published in: Organic & biomolecular chemistry (2022)
A Pd(ii)-catalyzed oxidative alkenylation of 4-hydroxycoumarins with maleimides for the synthesis of 4-hydroxy-3-maleimidecoumarins has been described. This methodology proceeds via C-H activation and C(sp2)-C(sp2) bond formation providing a series of alkenylated Heck-type products.
Keyphrases
  • room temperature
  • transition metal
  • solid state