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Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans.

Claudia BeiselAna Jordan-PaizSandra KöllmannAnnika Elise AhrenstorfBenedetta PadoanTanja BarkhausenMarylyn M AddoMarcus Altfeld
Published in: Biology of sex differences (2023)
Taken together, our data contribute to the understanding of sex differences in immune responses and may identify IRF5 as a potential therapeutic target to reduce harmful B cell-mediated immune responses in women.
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