Plasma Levels of Matrix Metalloproteinases 2 and 9 in Patients with Chronic Chagas Heart Disease and Systemic Arterial Hypertension: Correlation with TGF-Beta Plasma Levels.

Reinaldo B BestettiRenata Dellalibera-JovilianoEllen RizziGiselle F BonacioMilton Faria-JrRosemeire Furlan-DanielSuzeley Castro-França

Published in: Cardiology research and practice (2023)

MMP-2 and especially MMP-9 may play a role in the ECM remodeling process in patients with CCHD-SAH. TGF-Beta may counteract the MMP effect on the ECM remodeling process in patients with CCHD-SAH.

Keyphrases

arterial hypertension
cell migration
transforming growth factor
extracellular matrix
pulmonary hypertension
epithelial mesenchymal transition
signaling pathway
trypanosoma cruzi