Login / Signup

BRCA Mutation Carriers: Breast and Ovarian Cancer Screening Guidelines and Imaging Considerations.

Mai A ElezabyBrittany LeesKatherine E MaturenLisa BarroilhetKari B WisinskiSarina SchragerLee G WilkeElizabeth Sadowski
Published in: Radiology (2019)
Patients who carry the BRCA1 and BRCA2 gene mutations have an underlying genetic predisposition for breast and ovarian cancers. These deleterious genetic mutations are the most common genes implicated in hereditary breast and ovarian cancers. This monograph summarizes the evidence behind current screening recommendations, reviews imaging protocols specific to this patient population, and illustrates some of the imaging nuances of breast and ovarian cancers in this clinical setting.
Keyphrases
  • high resolution
  • genome wide
  • clinical practice
  • systematic review
  • case report
  • copy number
  • dna methylation
  • breast cancer risk
  • fluorescence imaging
  • mass spectrometry
  • childhood cancer