ChAdOx1 SARS-CoV-2 vaccination: A putative precipitant of adrenal crises.

Deirdre MaguireDavid S McLarenIrum RasoolPreet M ShahJulie LynchRobert D Murray

Published in: Clinical endocrinology (2021)

In individuals with adrenal insufficiency, adverse reactions to the initial dose of the ChAdOx1 SARS-CoV-2 vaccination can precipitate adrenal crises. We recommend that patients with AI should immediately increase their maintenance glucocorticoid dosage 2-3 fold on experiencing any symptoms in the initial 24 h following vaccination.

Keyphrases

sars cov
respiratory syndrome coronavirus
emergency department
physical activity
sleep quality
electronic health record
adverse drug