Genetic polymorphisms of PIP5K2A and course of schizophrenia.

Evgeniya G PoltavskayaOlga Yu FedorenkoNatalya M VyalovaElena G KornetovaNikolay A BokhanAnton J M LoonenSvetlana A Ivanova

Published in: BMC medical genetics (2020)

Our experimental data confirm that PIP5K2A is a genetic factor influencing the type of course of schizophrenia in Siberian population. Disturbances in the phosphatidylinositol pathways may be a possible reason for the transition to a more severe continuous course of schizophrenia.

Keyphrases

bipolar disorder
electronic health record
early onset
big data
machine learning
gene expression
dna methylation
protein kinase