Liver cancer: WISP3 suppresses hepatocellular carcinoma progression by negative regulation of β-catenin/TCF/LEF signalling.

Hong GaoFen-Fen YinDong-Xian GuanYu-Xiong FengQian-Wen ZhengXiang WangMin ZhuXue-Li ZhangShu-Qun ChengTian-Wei ChenHao JiangEr-Bin ZhangJing-Jing WangQian-Zhi NiYan-Mei YuanFeng-Kun ZhangNing MaHui-Jun CaoYi-Kang WangJing-Jing LiDong Xie

Published in: Cell proliferation (2019)

Our study showed that WISP3 suppressed the progression of HCC by negative regulation of β-catenin/TCF/LEF signalling, providing WISP3 as a potential therapeutic candidate for HCC.

Keyphrases

epithelial mesenchymal transition
cell proliferation
signaling pathway