Sudden cardiac death while waiting: do we need the wearable cardioverter-defibrillator?
Carsten IsraelIngo StaudacherChristophe LeclercqGiovanni Luca BottoDaniel ScherrAndreas FachFirat DuruMaura M ZyllaHugo A KatusDierk ThomasPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2022)
Sudden cardiac death (SCD) is the most frequent cause of cardiovascular death in industrialized nations. Patients with cardiomyopathy are at increased risk for SCD and may benefit from an implantable cardioverter-defibrillator (ICD). The risk of SCD is highest in the first months after myocardial infarction or first diagnosis of severe non-ischemic cardiomyopathy. On the other hand, left ventricular function may improve in a subset of patients to such an extent that an ICD might no longer be needed. To offer protection from a transient risk of SCD, the wearable cardioverter-defibrillator (WCD) is available. Results of the first randomized clinical trial investigating the role of the WCD after myocardial infarction were recently published. This review is intended to provide insight into data from the VEST trial, and to put these into perspective with studies and clinical experience. As a non-invasive, temporary therapy, the WCD may offer advantages over early ICD implantation. However, recent data demonstrate that patient compliance and education play a crucial role in this new concept of preventing SCD.
Keyphrases
- left ventricular
- heart failure
- end stage renal disease
- cardiac resynchronization therapy
- ejection fraction
- electronic health record
- newly diagnosed
- chronic kidney disease
- heart rate
- healthcare
- big data
- prognostic factors
- peritoneal dialysis
- clinical trial
- acute myocardial infarction
- mitral valve
- case report
- systematic review
- study protocol
- blood pressure
- aortic stenosis
- hypertrophic cardiomyopathy
- artificial intelligence
- patient reported outcomes
- quality improvement
- left atrial
- blood brain barrier
- brain injury
- ischemia reperfusion injury
- phase ii
- subarachnoid hemorrhage
- aortic valve
- case control