Impact of SARS-CoV-2 Infection on the Association Between Laboratory Tests and Severe Outcomes Among Hospitalized Children.
Jianling XieNathan KuppermannTodd Adam FlorinDaniel J TancrediAnna L FunkKelly KimMarina I SalvadoriAdriana Yock-CorralesNipam P ShahKristen A BreslinPradip P ChaudhariKelly R BergmannFahd A AhmadJasmine R NebhrajaniSantiago MintegiIker GangoitiAmy C PlintUsha R AvvaMichael A GardinerRichard MalleyYaron FinkelsteinStuart R DalzielMaala BhattNirupama KannikeswaranKerry CaperellCarmen CamposVikram J SabhaneyShu-Ling ChongMaren M LunoeAlexander J RogersSarah M BeckerMeredith L BorlandLaura F SartoriViviana PavlicichPedro B RinoAndrea K MorrisonMark I NeumanNaveen PoonaiNorma-Jean E SimonApril J KamMaria Y KwokClaudia R MorrisLaura PalumboLilliam AmbroggioNidhya NavanandanMichelle EckerleTerry P KlassenDaniel C PayneJonathan C CherryMuhammad WaseemAndrew C DixonIsabel Beneyto FerreStephen B FreedmanPublished in: Open forum infectious diseases (2023)
Specific laboratory parameters are associated with severe outcomes in SARS-CoV-2-infected children, and elevated serum procalcitonin, CRP, and D-dimer and low absolute lymphocyte and platelet counts were more strongly associated with severe outcomes in children testing positive compared with those testing negative.