Circulating tumor cells, circulating tumor DNA, and disease characteristics in young women with metastatic breast cancer.
Ami N ShahKristen J CarrollLorenzo GerratanaChenyu LinAndrew A DavisQiang ZhangSaya JacobBrian FinkelmanYoubin ZhangWenen QiangPaolo D'AmicoCarolina ReduzziWilliam J GradisharAmir BehdadMassimo CristofanilliPublished in: Breast cancer research and treatment (2021)
Our data reveal that premenopausal women diagnosed with MBC have unique clinical, pathologic, and molecular features when compared to their postmenopausal counterparts. Our results highlight FGFR1 inhibitors as potential therapeutics of particular interest among premenopausal women.
Keyphrases
- circulating tumor
- circulating tumor cells
- breast cancer risk
- metastatic breast cancer
- polycystic ovary syndrome
- cell free
- postmenopausal women
- pregnancy outcomes
- bone mineral density
- cervical cancer screening
- electronic health record
- genome wide
- pregnant women
- dna methylation
- early breast cancer
- locally advanced
- insulin resistance
- climate change
- data analysis