Combined SERS Microfluidic Chip with Gold Nanocone Array for Effective Early Lung Cancer Prognosis in Mice Model.
Yayun QianYuexing GuJialin DengZhaoying CaiYang WangRuoyu ZhouDongxu ZhuHongmei LuZheng WangPublished in: International journal of nanomedicine (2023)
This high-throughput SERS microfluidic chip has high sensitivity and specificity in the detection of ctDNA. This could be a potential tool for prognostic assessment of lung cancer treatment efficacy in future clinical applications.
Keyphrases
- high throughput
- label free
- gold nanoparticles
- sensitive detection
- single cell
- raman spectroscopy
- loop mediated isothermal amplification
- current status
- circulating tumor cells
- high fat diet induced
- circulating tumor
- real time pcr
- type diabetes
- silver nanoparticles
- metabolic syndrome
- risk assessment
- high resolution
- wild type
- skeletal muscle
- cell free