Association between Genetic Variants Linked to Premature Ovarian Insufficiency and Inflammatory Markers: A Cross-Sectional Study.

Mohammad Reza MirinezhadMaliheh AghsizadehMohammadreza Fazl MashhadiSara MoazediMaryam Mohammadi BajgiranHamideh GhazizadehShayan YaghoutiMahdi Mohammadian GhosooniMohammad Amin MohammadiElahe HasanzadehAli Ebrahimi DabaghArezoo Rastegarmoghadam EbrahimianEnsieh AkbarpourHabibollah EsmailyGordon A FernsTayebeh HamzehloeiAlireza Pasdar Majid Ghayour Mobarhan

Published in: International journal of fertility & sterility (2024)

There was a significant association of the genetic variants related to PM with oxidative stress and inflammatory markers (serum PAB, anti-hsp27 antibody, and hs-CRP). Accordingly, this seems to be an effective approach to predicting susceptible subjects for cardiovascular and mental disorders as well as various cancers.

Keyphrases

oxidative stress
heat shock protein
heat shock
particulate matter
air pollution
physical activity
dna damage
heat stress
heavy metals
polycyclic aromatic hydrocarbons
risk factors
diabetic rats
young adults
risk assessment
water soluble