Surgery-ineligible elderly patients with cutaneous squamous cell carcinoma of the head and neck region gain clinical benefit from definitive weekly hypofractionated radiotherapy.

Francesca De FeliceMaria SerponeCarlo Guglielmo CattaneoFederico Di GiammarcoAlberto FallicoAlessia Delle DonneMaura LanzilaoElisa VittiFrancesco MaramponDaniela MusioVincenzo TomboliniGiuseppe Minniti

Published in: Head & neck (2023)

Our study confirmed the satisfying efficacy and acceptable toxicity of definitive weekly hypofractionated RT for cHNSCC in elderly patients. Our results establish weekly hypofractionated scheduleas a promising treatment option for elderly patients with cHNSCC.

Keyphrases

radiation therapy
locally advanced
squamous cell carcinoma
middle aged
minimally invasive
radiation induced
rectal cancer
community dwelling
brain metastases
early stage
oxidative stress
lymph node metastasis
atrial fibrillation
coronary artery disease