Prognostic Utility of the Gleason Grading System Revisions and Histopathological Factors Beyond Gleason Grade.
Renata ZelicFrancesca GiunchiJonna FridfeldtJessica CarlssonSabina DavidssonLuca LianasCecilia MasciaDaniela ZugnaLuca MolinaroPer Henrik VincentGianluigi ZanettiOve AndrénLorenzo RichiardiOlof AkreMichelangelo FiorentinoAndreas PetterssonPublished in: Clinical epidemiology (2022)
The Gleason Grading revisions have improved PCa death prediction, likely due to classifying cribriform patterns, rather than poorly formed glands, as Gleason 4. Comedonecrosis, HGPIN and number of cores with ≥50% cancer further improve PCa death discrimination slightly.