Impact of heart rate, aortic compliance and stroke volume on the aortic regurgitation fraction studied in an ex vivo pig model.

Jan Christian ReilHiroyuki SaishoAntonia JockwerBuntaro FujitaLech PaluszkiewiczGert-Hinrich ReilStephan EnsmingerMichael ScharfschwerdtAnas Aboud

Published in: Open heart (2023)

Aortic compliance did not affect AR in the ex vivo porcine model of AR. RF was significantly reduced with increasing HR and SV. These results affirm that HR lowering and negative inotropic drugs should be avoided to treat severe AR.

Keyphrases

aortic valve
heart rate
heart rate variability
left ventricular
blood pressure
pulmonary artery
aortic dissection
transcatheter aortic valve replacement
aortic stenosis
atrial fibrillation
pulmonary hypertension
drug induced
ejection fraction