p53 Function and Dysfunction in Human Health and Diseases.
Gabriella D'OraziPublished in: Biomolecules (2023)
The p53 protein is a sequence-specific DNA-binding transcription factor that, in response to stressful stimuli, regulates gene expression related to multiple cellular functions including, but not limited to, cell cycle arrest, cell apoptosis, cell growth, DNA repair, cell metabolism, and the immune response [...].
Keyphrases
- dna binding
- dna repair
- human health
- transcription factor
- cell cycle arrest
- gene expression
- risk assessment
- immune response
- dna damage
- cell death
- pi k akt
- climate change
- dna damage response
- dna methylation
- single cell
- cell proliferation
- oxidative stress
- cell therapy
- amino acid
- signaling pathway
- dendritic cells
- toll like receptor
- protein protein
- binding protein
- genome wide identification
- stem cells
- drug induced
- bone marrow
- small molecule