Rare, Pathogenic Germline Variants in Fanconi Anemia Genes Increase Risk for Squamous Lung Cancer.

Myvizhi Esai Selvan Robert J KleinZeynep H Gümüş

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)

These findings can be used toward the development of a genetic diagnostic test in the clinic to identify SqCC high-risk individuals, who can benefit from personalized programs, improving prognosis.

Keyphrases

genome wide
copy number
high grade
chronic kidney disease
primary care
public health
dna repair
low grade
dna methylation
iron deficiency
oxidative stress