Explore potential disease related metabolites based on latent factor model.
Yongtian WangLiran JuanJiajie PengTao WangTianyi ZangYadong WangPublished in: BMC genomics (2022)
In this paper, a computational model is proposed for exploring metabolite-disease pairs and has good performance in predicting potential metabolites related to diseases through adequate validation. The results show that DLMPM has a better performance in prioritizing candidate diseases-related metabolites compared with the previous methods and would be helpful for researchers to reveal more information about human diseases.