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Explore potential disease related metabolites based on latent factor model.

Yongtian WangLiran JuanJiajie PengTao WangTianyi ZangYadong Wang
Published in: BMC genomics (2022)
In this paper, a computational model is proposed for exploring metabolite-disease pairs and has good performance in predicting potential metabolites related to diseases through adequate validation. The results show that DLMPM has a better performance in prioritizing candidate diseases-related metabolites compared with the previous methods and would be helpful for researchers to reveal more information about human diseases.
Keyphrases
  • ms ms
  • endothelial cells
  • healthcare
  • gene expression
  • genome wide
  • dna methylation
  • health information
  • single cell
  • climate change
  • drug induced