Reversal of cylindrical bronchial dilatations in a subset of adults with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor.
Paul CazierGuillaume ChassagnonThéo DhoteJennifer Da SilvaReem KanaanIsabelle HonoreNicolas CarlierMarie-Pierre RevelEmma CanniffClémance MartinPierre Regis BurgelPublished in: The European respiratory journal (2024)
Although bronchial dilatations are generally considered irreversible, ETI was associated with reversal, which was limited to the cylindrical bronchial dilatations subtype, and occurred in a small subset of awCF. Initiating ETI earlier in life may reverse early bronchial dilatations.
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