Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study.
Alexis TabahNiccolò BuettiQuentin StaiqulyStéphane RucklyMurat AkovaAbdullah Tarik AslanMarc LeoneAndrew Conway MorrisMatteo BassettiKostoula ArvanitiJeffrey LipmanRicard FerrerHaibo QiuJosé-Artur PaivaPedro PovoaLiesbet De BusJan J De WaeleFarid ZandShreyas GutteAdel AlsisiKhalid AbidiHendrik BrachtYoshiro HayashiKyeongman JeonMuhammed ElhadiFrançois BarbierJean-François Timsitnull nullPublished in: Intensive care medicine (2023)
HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes.
Keyphrases
- antimicrobial resistance
- gram negative
- intensive care unit
- end stage renal disease
- ejection fraction
- newly diagnosed
- multidrug resistant
- prognostic factors
- healthcare
- staphylococcus aureus
- emergency department
- risk factors
- cardiovascular disease
- cardiovascular events
- adipose tissue
- bone marrow
- metabolic syndrome
- coronary artery disease
- case report
- mesenchymal stem cells
- mechanical ventilation
- adverse drug
- electronic health record
- patient reported
- replacement therapy