High plasma 25-hydroxyvitamin D and high risk of nonmelanoma skin cancer: a Mendelian randomization study of 97 849 individuals.

U C WinsløwB G NordestgaardShoaib Afzal

Published in: The British journal of dermatology (2018)

Genetically determined high 25(OH)D levels did not appear to protect against NMSC, whereas high plasma 25(OH)D concentrations were associated with an observational high risk of NMSC. Thus, the observational association likely reflects confounding by sun exposure rather than causality.

Keyphrases

skin cancer
emergency department
adverse drug
electronic health record