Pretargeted radioimmunoimaging with a biotinylated D-D3 construct and 99mTc-DTPA-biotin: strategies for early diagnosis of small cell lung cancer.

Shengming DengShengming DengYizhen ShiYichi XieJiaxi YouWei WangHong HuangZengli Liu

Published in: The Journal of international medical research (2021)

In contrast to directly labeled D-D3, pretargeting technology displayed specific enhancement and signal amplification in tumors, which could increase the target tumor uptake of 99mTc and provide a new approach for the early diagnosis of SCLC.

Keyphrases

small cell lung cancer
magnetic resonance
nucleic acid
pet imaging
brain metastases
contrast enhanced