Ghrelin mitigates β-cell mass loss during insulitis in an animal model of autoimmune diabetes mellitus, the BioBreeding/Worcester rat.

Gloria Baena-NietoIsabel M Lomas-RomeroRosa M MateosNoelia Leal-CosmeGonzalo Perez-AranaManuel Aguilar-DiosdadoCarmen SegundoAlfonso María Lechuga-Sancho

Published in: Diabetes/metabolism research and reviews (2016)

Ghrelin promotes β-cell viability and function through diverse mechanisms that may have significant implications for diabetes prevention, therapy and also transplant success of both islets and complete pancreas. Copyright © 2016 John Wiley & Sons, Ltd.

Keyphrases

glycemic control
type diabetes
single cell
cell therapy
cardiovascular disease
multiple sclerosis
oxidative stress
growth hormone
radiation induced
drug induced
skeletal muscle
insulin resistance
adipose tissue