Pre-flight exercise and bone metabolism predict unloading-induced bone loss due to spaceflight.

Leigh Gabel Anna-Maria LiphardtPaul A HulmeMartina HeerSara R ZwartJean D SibongaScott M Smith Steven K Boyd

Published in: British journal of sports medicine (2021)

Findings highlight the fundamental relationship between mission duration and bone loss. Pre-flight markers of bone turnover and exercise history may identify crewmembers at greatest risk of bone loss due to unloading and may focus preventative measures.

Keyphrases

bone loss
high intensity
physical activity
bone mineral density
resistance training
high glucose
body composition
drug induced
endothelial cells
oxidative stress