Variations in germ cell tumor histology by age and implications for cancer-specific survival among pediatric and adult males: A population-based study.
J Bradley MasonArnav SrivastavaNicholas J LanzottiJeffrey L EllisHeather N Di CarloJohn P GearhartDiana K BowenMohit GuptaMaria M PickenGopal N GuptaHiten D PatelPublished in: Urologic oncology (2024)
Histology of GCTs vary by age with yolk sac tumors and teratoma predominating for male patients 0 to 4 years, mixed GCT for 12 to 18 years, and seminoma for 19 to 40 years. Pediatric patients with NSGCT had higher CSS than their adult counterparts. Mixed GCT represented an increasing proportion of GCT over the study period. Age, stage, and histology impact CSS in both pediatric and adult populations.