High-Fat and High-Sucrose Diets Impair Time-of-Day Differences in Spatial Working Memory of Male Mice.
Jennifer A DavisJodi R PaulLaura J McMeekinShelly R NasonJessica P AntipenkoStefani D YatesRita M CowellKirk M HabeggerKaren L GamblePublished in: Obesity (Silver Spring, Md.) (2020)
Taken together, these results suggest that both HFD and HSD induce a loss of day/night performance in spatial working memory and synaptic plasticity as well as trigger a cascade of changes that include disruption to the hippocampal molecular clock.