Radical esophagectomy for stage II and III thoracic esophageal squamous cell carcinoma followed by adjuvant radiotherapy with or without chemotherapy: Which is more beneficial?
Bingwen ZouYan TuDuwen LiaoYong XuJin WangMeijuan HuangLi RenJiang ZhuYouling GongYongmei LiuLin ZhouXiaojuan ZhouFeng PengYou LuPublished in: Thoracic cancer (2020)
Postoperative chemoradiotherapy led to one- and three-year overall survival benefits along with an obvious increase in treatment side effects for stage II to III TESCC patients, with no further improvement in five-year survival. However, the chemoradiotherapy benefits mainly favor stage III,number of resected lymph nodes less than 15, younger (less than 60 years old) and smoking patients.
Keyphrases
- locally advanced
- lymph node
- rectal cancer
- early stage
- end stage renal disease
- prognostic factors
- squamous cell carcinoma
- neoadjuvant chemotherapy
- ejection fraction
- newly diagnosed
- radiation therapy
- chronic kidney disease
- patients undergoing
- spinal cord
- patient reported outcomes
- spinal cord injury
- robot assisted
- sentinel lymph node
- radiation induced
- combination therapy
- replacement therapy