Risk for Health Events After Deprescribing Acetylcholinesterase Inhibitors in Nursing Home Residents With Severe Dementia.
Joshua D NiznikXinhua ZhaoMeiqi HeSherrie L AspinallJoseph T HanlonLaura C HansonDavid A NaceJoshua M ThorpeCarolyn T ThorpePublished in: Journal of the American Geriatrics Society (2019)
Deprescribing AChEIs was not associated with a significant increase in the likelihood for all-cause negative events and was associated with a reduced likelihood of falls and fractures in older NH residents with dementia. Our findings suggest that deprescribing AChEIs is a reasonable approach to reduce the risk of serious falls or fractures without increasing the risk for all-cause events. J Am Geriatr Soc 68:699-707, 2020.