Radiation-induced accelerated aging of the brain vasculature in young adult survivors of childhood brain tumors.
Tiina Maria RemesMaria Helena Suo-PalosaariPäivi K T KoskenkorvaAnna K SutelaSanna-Maria Toiviainen-SaloPekka M ArikoskiMikko O ArolaVesa-Pekka HeikkiläMika KapanenPäivi Maria LähteenmäkiTuula R I LönnqvistHannele NiiniviitaTytti M-L PokkaLiisa PorraV Pekka RiikonenJan SeppäläKirsti H SirkiäAntti VanhanenHeikki M J RantalaArja H Harila-SaariMarja K OjaniemiPublished in: Neuro-oncology practice (2020)
Treating CBTs with radiotherapy increases the risk of early CVD and WMHs in young adult survivors. These results suggest an urgent need for investigating CVD prevention in CBT patients.
Keyphrases
- young adults
- radiation induced
- end stage renal disease
- childhood cancer
- radiation therapy
- newly diagnosed
- chronic kidney disease
- ejection fraction
- peritoneal dialysis
- squamous cell carcinoma
- resting state
- locally advanced
- functional connectivity
- patient reported outcomes
- early life
- subarachnoid hemorrhage
- patient reported