One-Enzyme Triple Catalysis: Employing the Promiscuity of Horseradish Peroxidase for Synthesis and Functionalization of Well-Defined Polymers.

We demonstrate a new concept in polymer chemistry that the promiscuity of enzymes, as represented by horseradish peroxidase, can be employed for RAFT polymerization and thiol-ene and Diels-Alder reactions to synthesize well-defined functional polymers, via three different catalytic reactions mediated by one single enzyme.