High-Risk Human Papillomavirus Testing, Genotyping, and Histopathologic Follow-up in Women With Abnormal Glandular Cells on Papanicolaou Tests.

Tao ZuoAngelique W LeviQiongqiong LinRita Abi-RaadAdebowale J AdeniranGuoping Cai

Published in: American journal of clinical pathology (2021)

Our data demonstrate that in women with an AGC Pap interpretation, a positive hrHPV result, especially type 16 or 18, is associated with an increased risk of developing cervical CIN2-3 or higher lesions, suggesting potential implications of hrHPV testing for the management of patients with an AGC result on a Pap test.

Keyphrases

induced apoptosis
cell cycle arrest
high throughput
genome wide
endoplasmic reticulum stress
cell death
risk assessment
signaling pathway
machine learning
cell proliferation
deep learning
genetic diversity
artificial intelligence
single cell