Using DEPendency of association on the number of Top Hits (DEPTH) as a complementary tool to identify novel colorectal cancer susceptibility loci.

John Lai Chi Kuen Wong Daniel Francis Schmidt Miroslaw K Kapuscinski Karen Alpen Robert J MacInnis Daniel D Buchanan Aung-Ko Win Jane C Figueiredo Andrew T Chan Tabitha A Harrison Michael Hoffmeister Emily White Loic Le Marchand Rish K Pai Ulrike Peters John L Hopper Mark E Jenkins Enes Makalic

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)

DEPTH has potential as a powerful complementary tool to conventional GWAS analyses for discovering susceptibility regions within the genome.

Keyphrases

optical coherence tomography
genome wide
genome wide association study
dna methylation
human health
genome wide association