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LSTrAP-Crowd: prediction of novel components of bacterial ribosomes with crowd-sourced analysis of RNA sequencing data.

Benedict HewQiao Wen TanWilliam GohJonathan Wei Xiong NgMarek Mutwil
Published in: BMC biology (2020)
We identified genes related to protein synthesis in common bacterial pathogens and thus provide a resource of potential antibiotic development targets for experimental validation. The data can be used to explore additional vulnerabilities of bacteria, while our approach demonstrates how the processing of gene expression data can be easily crowd-sourced.
Keyphrases
  • gene expression
  • electronic health record
  • big data
  • dna methylation
  • single cell
  • genome wide
  • transcription factor
  • data analysis
  • antimicrobial resistance
  • gram negative
  • bioinformatics analysis