Identifying the Dominant Contribution of Human Cytochrome P450 2J2 to the Metabolism of Rivaroxaban, an Oral Anticoagulant.
Tingting ZhaoYanwei ChenDalong WangLiyan WangPeipei DongShan ZhaoChangyuan WangQiang MengHuijun SunKexin LiuJingjing WuPublished in: Cardiovascular drugs and therapy (2021)
CYP2J2 dominated the hydroxylation of rivaroxaban, which may provide new insight into clinical drug interactions involving rivaroxaban.