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Recent development in fibrin nanoparticles (F-NPs) and in vitro study targeting of oral cancer.

Rethinam Senthil
Published in: Natural product research (2024)
Fibrin is limited by some factors that limit its clinical applicability, such as rapid degradation, poor water solubility, and low oral bioavailability. However, they can be applied clinically when they are included in the development of biocompatible fibrin nanoparticles (F-NPs). In this present study, F-NPs were prepared using co-precipitation techniques and In vitro studies using oral cancer cell lines also proved the anticancer activity of F-NPs. The study devised a technology for converting slaughterhouse waste into a value-added material such as anti-cancer F-NPs.
Keyphrases
  • drug delivery
  • ionic liquid
  • cancer therapy
  • water soluble