ERK5 plays an essential role in gestational beta-cell proliferation.
Congde ChenSuichun WuXiaokun LinDazhou WuShane FischbachXiangwei XiaoPublished in: Cell proliferation (2017)
Extracellular-signal-regulated kinase 5 plays an essential role in the gestational augmentation of beta-cell proliferation. ERK5 may be a promising target for increasing beta-cell mass in diabetes patients.
Keyphrases
- cell proliferation
- pi k akt
- weight gain
- signaling pathway
- pregnant women
- cell cycle
- end stage renal disease
- type diabetes
- ejection fraction
- newly diagnosed
- cardiovascular disease
- single cell
- prognostic factors
- birth weight
- peritoneal dialysis
- transcription factor
- body mass index
- mesenchymal stem cells
- insulin resistance
- tyrosine kinase
- gestational age