Neurovascular coupling alterations in type 2 diabetes: a 5-year longitudinal MRI study.
Yang ZhangXiaolu ZhangGuangyang MaWen QinJiayang YangJiahui LinQuan ZhangPublished in: BMJ open diabetes research & care (2021)
This study suggests that T2DM may accelerate neurovascular coupling impairment in specific brain regions (the left insula), contributing to memory decline. This study implies that the mReHo:mCBF ratio is a potential imaging marker for detecting neurovascular changes.