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Fibroblast growth factor 23, glucose homeostasis and incident diabetes: findings of two cohort studies.

Amarens van der VaartCoby EelderinkAndré P van BeekStephan J L BakkerPeter R van DijkMartin H de Borst
Published in: The Journal of clinical endocrinology and metabolism (2023)
Glucose loading has phosphate-independent effects on FGF23 and, vice versa, FGF23 is associated with glucose, insulin and proinsulin levels and obesity. These findings suggest cross-talk between FGF23 and glucose homeostasis, which may promote susceptibility to incident diabetes.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • blood glucose
  • glycemic control
  • insulin resistance
  • adipose tissue
  • body mass index
  • high fat diet induced
  • skeletal muscle