Patterns of CMR measured longitudinal strain and its association with late gadolinium enhancement in patients with cardiac amyloidosis and its mimics.
Lynne K WilliamsJulian F ForeroZoran B PopovicDermot PhelanDiego DelgadoHarry RakowskiBernd J WinterspergerPaaladinesh ThavendiranathanPublished in: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance (2017)
The presence of marked "relative apical sparing" of LS along with a significant reduction in global LS seen in patients with CA on CMR cine analysis may provide an additional tool to differentiate CA from other cause of LVH. The concomitant presence of a base to apex gradient in quantitative LGE burden suggests that the regional strain gradient may be at least partially explained by the burden of amyloid deposition and fibrosis.