Aberrant growth of the anterior cranial base relevant to severe midface hypoplasia of Apert syndrome.
Bong Kuen ChaDong Soon ChoiIn San JangHyun Tae YookSeung Youp LeeSang Shin LeeSuk Keun LeePublished in: Maxillofacial plastic and reconstructive surgery (2018)
Taken together, the Apert syndrome patient, 9 years old, showed retarded growth of the anterior cranial base affecting severe midface hypoplasia, which resulted in a hypoplastic nasal septum axis, retruded zygomatic axes, and retarded growth of the maxilla and palate even after frontal calvaria distraction osteotomy 8 years ago. Therefore, it was suggested that the severe midface hypoplasia and dysostotic facial profile of the present Apert syndrome case are closely relevant to the aberrant growth of the anterior cranial base supporting the whole oro-facial and forebrain development.