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Extracellular vesicles from myelodysplastic mesenchymal stromal cells induce DNA damage and mutagenesis of hematopoietic stem cells through miRNA transfer.

Mathieu MeunierAudrey GuttinSarah AnceletDavid LaurinJohanna ZannoniChristine LefebvreSylvie TondeurVirginie PersoonsMylène PezetKarin Pernet-GallayFlorent ChuffartSophie RousseauxQuentin TestardJulien ThevenonClaire JouzierJean-François DeleuzeKarine LaulagnierRémy SadoulChristine ChatellardPierre HainautBenoît PolackJean-Yves CahnJean-Paul IssartelSophie Park
Published in: Leukemia (2020)
Keyphrases
  • bone marrow
  • dna damage
  • stem cells
  • crispr cas
  • dna repair
  • oxidative stress
  • mesenchymal stem cells
  • cell therapy
  • acute myeloid leukemia