Login / Signup

Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver.

Sonia García-CalzónAlexander PerfilyevVille MännistöVanessa D de MelloEmma NilssonJussi PihlajamäkiCharlotte Ling
Published in: Clinical epigenetics (2017)
Our study supports that metformin decreases DNA methylation of metformin transporter genes in the human liver. Moreover, higher methylation levels in these genes associate with hyperglycaemia and obesity.
Keyphrases
  • genome wide
  • dna methylation
  • type diabetes
  • gene expression
  • genome wide identification
  • copy number
  • bioinformatics analysis
  • metabolic syndrome
  • healthcare
  • weight loss
  • genome wide analysis
  • adverse drug
  • drug induced