Therapeutic lag: Is treatment effect delayed in progressive MS?

Noemi MontobbioFrancesca Bovis Alessio Signori Marta Ponzano Irene Schiavetti Maria Pia Sormani

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)

The assumption of a delayed treatment effect improved the fit to the data of the two examined RCTs, uncovering a significant, although shifted, benefit of treatment.

Keyphrases

mass spectrometry
machine learning
combination therapy
electronic health record
replacement therapy