p53 Inhibits Bmi-1-driven Self-Renewal and Defines Salivary Gland Cancer Stemness.
Christie Rodriguez-RamirezZhaocheng ZhangKristy A WarnerAlexandra E HerzogAndrea MantessoZhixiong ZhangEuisik YoonShaomeng WangMax S WichaJacques Eduardo NörPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Collectively, these results demonstrate that p53 defines the stemness of MEC and suggest that therapeutic activation of p53 might have clinical utility in patients with salivary gland MEC.