Incidence and progression of atrial fibrillation in patients with and without heart failure using mineralocorticoid receptor antagonists: a meta-analysis.

Thalys Sampaio RodriguesLevindo Jose Garcia QuartoSavio Carvalho NogueiraAnoop N KoshyRajiv MahajanPrashanthan SandersElif I EkinciLouise M BurrellOmar FarouqueHan S Lim

Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2024)

MRA use is associated with a reduction in AF risk, especially AF progression. A prominent effect is seen in patients with heart failure, further augmented by therapy duration. Prospective trials are warranted to evaluate MRA use as upstream therapy for preventing this common arrhythmia.

Keyphrases

atrial fibrillation
heart failure
catheter ablation
left atrial
oral anticoagulants
left atrial appendage
contrast enhanced
direct oral anticoagulants
risk factors
percutaneous coronary intervention
stem cells
magnetic resonance imaging
cardiac resynchronization therapy
cell therapy